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Quality of life measurement in pancreatic cancer patients : a randomized trial of percutaneous splanchnic nerve neurolysis versus endoscopic ultrasound guide celiac plexus neurolysis

Quality of life measurement in pancreatic cancer patients : a randomized trial of percutaneous splanchnic nerve neurolysis versus endoscopic ultrasound guide celiac plexus neurolysis S-celiac plexus neurolysis

Status
Unknown
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220512002
Enrollment
60
Registered
2022-05-12
Start date
2022-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer patient with abdominal pain. pancreatic cancer, cancer pain, splanchnic nerve neurolysis, neurolysis, celiac plexus neurolysis, abdominal pain

Interventions

Percutaneous splanchnic nerve neurolysis under fluoroscopic guidance. Patient keep in prone position. 5 ml of 2% lidocaine was infiltrated before spinal needles 22G were inserted from back to splanchn
Experimental Procedure/Surgery,Experimental Procedure/Surgery
percutaneous splanchnic nerve neurolysis,endoscopic ultrasound guide celiac plexus neurolysis

Sponsors

Ratchadapisek Research Funds
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. age above 18 years 2. Pancreatic cancer patient with numeric rating scale more than 4 from total 10 score 3. patient can make decision to apply the study by themselves and cooperate with the protocol 4. Patient who can follow up for 1 month after procedure

Exclusion criteria

Exclusion criteria: 1. Allergic to agent in study 2. Refuse to join study 3. gut obstruction 3.coagulopathy or use antiplatelet or anticoagulant drug that can not control bleeding risk 4. Pregnancy 5. uncontrol underlying disease sush as uncontrol hypertension, heart failure 6. uncommunicative patient 7. severe systemic infection, local infection in procedure area 8. patient who have pain in other area except abdominal pain 9. Previous percutaneous splanchnic nerve neurolysis or endoscopic ultrasound guide celiac plexus neurolysis

Design outcomes

Primary

MeasureTime frame
quality of life 1 week and 1 month after procedure Functional Assessment of Cancer Therapy Hepatobiliary

Secondary

MeasureTime frame
pain score in numeric rating scale 1 week and 1 month after procedure numeric rating scale ,opioid consumption 1 week and 1 month after procedure oral morphine equivalence

Countries

Thailand

Contacts

Public ContactMarvin Thepsoparn

Chulalongkorn hospital

marvin.thep@gmail.com0858131830

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026