dexamethasone 4 mg ,5 mg and 6 mg, adverse neonatal and maternal outcomes dexamthasone, 4mg, 5 mg, 6 mg, adverse outcome, maternal outcomes, neonatal outcomes
Conditions
Interventions
Dexamthasone 5 mg will be administrated in pregnant women 320-366 weeks of gestation.,Dexamthasone 4 mg will be administrated in pregnant women 320-366 weeks of gestation.,Dexamthasone 6 mg will be ad
Dexamethasone 5 mg,Dexamethasone 4 mg,Dexamethasone 6 mg
Sponsors
Faculty of Medicine, Siriraj Hospital, Mahidol University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Pregnant women who gave birth in the gestational age of 320-366 weeks by calculating the gestational age from the menstrual history and ultrasound during the first trimester. 2. Singleton pregnancy 3. Pregnant women with preterm labor 4. Pregnant women who signed their consent to participate in the research
Exclusion criteria
Exclusion criteria: 1. Pregnant women under 18 years of age 2. Pregnant women who have received steroids before 32 weeks of gestation 3. Pregnant women with steroid allergy or have an infection 4. Pregnant women with gestational diabetes include gestational diabetes mellitus and pregestational diabetes mellitus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RDS in preterm infants 320-366 weeks gestation at 12 months after end of the intervention More than 60 breaths per minute, flaring, grunting, retraction of chest, and oxygen for more than 2 hours postpartum. | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse maternal outcomes at 30 days after intervention maternal fever, maternal infection,adverse neonatal outcomes at 30 days after intervention neonatal fever, neonatal hypotension,respiratory complications except RDS | — |
Countries
Thailand
Contacts
Public ContactSaifon Chawanpaiboon
Faculty of Medicine, Siriraj Hospital, Mahidol University
Outcome results
None listed