Pneumatization of the maxillary sinus in patients with healthy medical conditions requiring two-staged maxillary sinus augmentation. Platelet rich fibrin, maxillary sinus floor augmentation, gene expression, xenograft
Conditions
Interventions
Mixture of PRF and xenograft was used for the experimental group.,Xenograft alone was used for the control group.
Experimental Procedure/Surgery,Placebo Comparator Procedure/Surgery
PRF,Control
Sponsors
Faculty of Dentistry, Chiang Mai university,
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. two-staged maxillary sinus augmentation was required prior to implant placement, 2. Systemically healthy, 3. Residual alveolar bone height of less than 5mm, 4. Age over 18 years.
Exclusion criteria
Exclusion criteria: 1. Patients with medical disorders that may impair bone healing, such as uncontrolled diabetes, hypertension, or those taking bisphosphonate or steroid therapy, 2. Smokers, 3. History of maxillary sinusitis, 4.History of reconstructive or previous implant surgery, 5. Being edentulous less than 3 months, 6. Maxillary sinus septum.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| histology, histomorphometry parameters after 6 months of maxillary sinus augmentation area of new bone formation, residual bone graft, contact length between newly formed bone and residual bone graft,gene expression level after 6 months of maxillary sinus augmentation realtime RT-PCR | — |
Secondary
| Measure | Time frame |
|---|---|
| linear analysis of radiographic evaluation post-operative 7 days and post-operative 6 months of maxillary sinus augmentation distance between lowest point of alveolar bone to highest point of grafted bone,volumetric analysis of radiographic evaluation post-operative 7 days and post-operative 6 months of maxillary sinus augmentation segmentation technique in CBCT scan | — |
Countries
Thailand
Contacts
Public ContactKathawut Tachasuttirut
Chiang Mai University
Outcome results
None listed