The Effectiveness of Local Wound Infiltration with Morphine, Ketorolac, and Bupivacaine Following Tibial Osteotomy in Pediatric Patients: A Randomized Controlled Trial

Status

Unknown

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220510009

Enrollment

Registered

2022-05-10

Start date

2022-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain after surgery pain score pediatric tibial surgery

Interventions

bupivacaine (control group) ,bupivacaine, ketorolac, and morphine (combination group)

Active Comparator Drug,Active Comparator Drug

control group,combination group

Eligibility

Sex/Gender

All

Age

6 Years to 15 Years

Inclusion criteria

Inclusion criteria: Aged 1-15 years Undergoing tibial osteotomy at Siriraj hospital Obtained consent from a guardian two surgeons

Exclusion criteria

Exclusion criteria: Pre-existing pain e.g. from fracture, infection, etc. Loss of sensation Bleeding disorder Allergy to NSAIDs, morphine, bupivacaine, paracetamol eGFR < 90 mL/min/1.73 m2 Language barrier

Design outcomes

Primary

Measure	Time frame
morphine consumption 48 h mg	—

Secondary

Measure	Time frame
pain score 48 h VAS	—

Countries

Thailand

Contacts

Public ContactPiyanuch Musikachart

Faculty of Medicine Siriraj Hospital

bangpiya@hotmail.com0858115696

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026