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Effectiveness of local wound infiltration of morphine, ketorolac, and bupivacaine following tendon surgery in pediatric patients: A randomized controlled trial

Effectiveness of local wound infiltration of morphine, ketorolac, and bupivacaine following tendon surgery in pediatric patients: A randomized controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220504001
Enrollment
106
Registered
2022-05-04
Start date
2021-08-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children age 1-15 years who will undergo tendon surgery (such as Achilles tendon tenotomy, hamstring tenotomy, adductor tenotomy and tendon transfer) Postoperative pain control, children, tendon surgery, opioid consumption

Interventions

0.25%buipivacaine dose 0.5 ml/kg local injection after finish operation,morphine dose 0.05 mg/kg, ketorolac dose 0.5 mg/kg and 0.25%buipivacaine dose 0.5 ml/kg local injection after finish operation
Active Comparator Drug,Experimental Drug
0.25%buipivacaine ,morphine, ketorolac and 0.25%buipivacaine

Sponsors

Siriraj hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children age 1-15 years who will undergo tendon surgery (such as Achilles tendon tenotomy, hamstring tenotomy, adductor tenotomy and tendon transfer) No previous pain before operation

Exclusion criteria

Exclusion criteria: History of drug allergy to bupivacaine, ketorolac, morphine, paracetamol and ibuprofen History of bleeding disorder History of abnormal kidney function

Design outcomes

Primary

MeasureTime frame
Postoperative pain after tendon surgery in children Every 4 hours postoperative until 48 hours Pain score (CHEOPS or NRS)

Secondary

MeasureTime frame
Morphine consumption 48 hours postoperative Total morphine consumption (mg),Complication from morphine 48 hours postoperative Complication from morphine

Countries

Thailand

Contacts

Public ContactJidapa Wongcharoenwatana

Faculty of Medicine Siriraj Hospital, Mahidol University

jidapa.wongcha@gmail.com0819374082

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026