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The effect of consumption probiotic chocolate containing Lactobacillus plantarum Dad-13 on gut microbiota, the fecal SCFA and pH of undernourished children in Lombok

A Randomized Double-Blind Trial on the Effects on Consuming Probiotic Chocolate containing Lactobacillus plantarum Dad-13 on Gut microbiota, Fecal SCFA and pH of Undernourished Children in Lombok

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220425001
Enrollment
60
Registered
2022-04-25
Start date
2019-06-28
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Undernourished children Malnutrition Probiotics Chocolate Gastrointestinal Microbiome Fatty Acids, Volatile

Interventions

Participants consumed the probiotic chocolate containing chocolate and probiotic indigenous L. plantarum Dad-13 every day for 10 days,Participants consumed the same chocolate as the probiotic chocolat
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
Probiotic chocolate containing probiotic indigenous L. plantarum Dad-13 ,Chocolate

Sponsors

Faculty of Agricultural Technology, Universitas Gadjah Mada
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 12 Years

Inclusion criteria

Inclusion criteria: Domicile in Belanting, Lombok Timur Able to read, understand and agree with the research provisions Z-score between -3 to < -2 SD based on BMI/Age Physically and mentally healthy

Exclusion criteria

Exclusion criteria: Consume alcohol Have digestive disorder, Take antibiotics Take supplements or immunoregulators Have gastrointestinal surgery history Have a history of allergy to the components of probiotic products or placebo Consuming other probiotic products aside from the research product Smokes

Design outcomes

Primary

MeasureTime frame
Gut microbiota composition 5 months using 16S rRNA sequencing

Secondary

MeasureTime frame
Fecal pH analysis 5 months pH meter ,Fecal short chain fatty acids analysis 5 months Gas chromatography

Countries

Indonesia

Contacts

Public ContactEndang Rahayu

Faculty of Agricultural Technology, Universitas Gadjah Mada

endangsrahayu@ugm.ac.id08122690013

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026