Post-COVID-19 interstitial lung disease Post-COVID-19 interstitial lung disease Post-COVID-19 ILD
Conditions
Interventions
HRCT abnormalities which indicate the presence of ILD,No evidence of ILD on HRCT
Diagnostic,Diagnostic
Post-COVID-19 interstitial lung disease,No post-COVID-19 interstitial lung disease
Sponsors
Routine to Research (R2R) Project, Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age more than or equal to 18 years 2. Confirm diagnosis of COVID-19 infection by RT-PCR of respiratory specimens 3. Confirm diagnosis of pneumonia 4. Hospitalized in Siriraj Hospital (general wards and critical care units) 5. Persistent respiratory symptom after 6 months of date of symptom with abnormal chest X-ray
Exclusion criteria
Exclusion criteria: 1. Pre-existing chronic lung diseases, including interstitial lung disease and bronchiectasis 2. Pregnant woman 3. No persistent respiratory symptom after 6 months of date of symptom 4. Normal chest X-ray after 6 months of date of symptom 5. Unable to perform high resolution computed tomography 6. Unable to perform pulmonary function tests 7. Presence of contraindication for pulmonary function tests 8. Deny to enroll
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-COVID-19 interstitial lung disease 6 months after date of symptoms Medical record and HRCT official report | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function tests and associated factor of severity of impairment 6 months after date of symptoms Official report of pulmonary function tests,Quality of life and associated factor of severity of impairment 6 months after date of symptoms Questionaire (EQ-5D-5L and SGRQ),Changes of HRCT abnormalities 6 months after date of symptoms HRCT official report and radiologist consultation | — |
Countries
Thailand
Contacts
Public ContactSupparerk Disayabutr
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed