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Restrict volume & vasopressor resuscitation in Pediatric sepsis

Time to vasoactive agents initiation, restricted volume resuscitation effect on fluid balance and clinical outcomes in children with septic shock

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20220419007
Enrollment
200
Registered
2022-04-19
Start date
2019-08-12
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric severe sepsis and need hemodynamic resuscitation. Resticted volume resuscitation, severe sepsis, pediatric, vasopressor

Interventions

Restricted volume resuscitation and early vasopressor,Usual Care sepsis
Treatment,Treatment
Children with severe sepsis who required fluid resuscitation less than 40 cc/kg ,Required fluid more than 40 cc/kg and vasopressors

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
1 Months to 18 Years

Inclusion criteria

Inclusion criteria: All pediatric patients aged between one month to 18 years admitted to the PICU with septic shock who received at least one vasoactive agent were enrolled. Those with congenital heart disease with congestive heart failure, chronic kidney disease, and/or signs of volume overload, palliative treatment, and missing data collection were excluded

Exclusion criteria

Exclusion criteria: Those with congenital heart disease with congestive heart failure, chronic kidney disease, and/or signs of volume overload, palliative treatment, and missing data collection were excluded

Design outcomes

Primary

MeasureTime frame
Mortality end of 28 days of PICU admission number of death in PICU

Secondary

MeasureTime frame
Morbidity End of 28 PICU admission Length of PICU stay

Countries

Thailand

Contacts

Public ContactRujipat Samransamruajkit

King Chulalongkorn Memorial Hospital

rujipatrs@gmail.com022564951

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026