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Furosemide for prevention 72 hours postpartum hypertension in women with preeclampsia with severe features: A randomized controlled trial

Furosemide for prevention 72 hours postpartum hypertension in women with preeclampsia with severe features: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220419002
Enrollment
78
Registered
2022-04-19
Start date
2021-06-23
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persistent postpartum hypertension in preeclampsia with severe feature Preeclampsia, Postpartum period, Hypertension

Interventions

Furosemide dose 20 mg oral once 3 days half tab of Furosemide 40 mg,Placebo half tab oral once 3 days
Experimental Drug,Placebo Comparator Drug
Furosemide,Placebo

Sponsors

None listed

Eligibility

Sex/Gender
Female
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Women who's 15 years old or more with preeclampsia with severe features who was undergone termination of pregnancy at 24 weeks' gestation or more

Exclusion criteria

Exclusion criteria: 1.pre-existing hypertension or taking antihypertensive medication 2.hypokalemia 3.history used of diuretic drug 4.unstable vital signs 5.allergy to furosemide or sulfonylurea 6.severe postpartum complication

Design outcomes

Primary

MeasureTime frame
Blood pressure at 72 hours postpartum 72 hours postpartum Blood pressure measurement in mmHg,Persistent hypertension at 72 hours postpartum 72 hours postpartum systolic blood pressure 140 mmHg or more OR diastolic blood pressure 90 mmHg or more

Secondary

MeasureTime frame
the use of antihypertensive medication at hospital discharge patient's antihypertensive drug at hospital discharge,Milk ejection performance 3 days postpartum milk ejection score (0-4),Hospital stay after termination at hospital discharge number of days,Potassium level 6 hours after 2nd tab administration blood chemistry lab,creatinine level 6 hours after 2nd tab administration blood chemistry lab

Countries

Thailand

Contacts

Public ContactChayanid Detwongya

Maharat Nakhon Ratchasima Hospital

chayanid.png@gmail.com66858682799

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026