Infections eg. septicemia, pneumonia, urinary tract infection, intra-abdominal infection, Skin and soft tissue infection, CNS infection infection, Enterobacterales, mortality, treatment failure, risk factors
Conditions
Interventions
Children infected with Ceftriaxone-resistant Enterobacterales who was treated infection by carbapenems and non-carbapenems
Treatment
non-carbapenem group, carbapenem group
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
1 Hours to 15 Years
Inclusion criteria
Inclusion criteria: Children aged 0 to 15 years who infected with ceftriaxone-resistant Enterobacterales in any sources of infection that were diagnosed during January 2016 to December 2021. Also received at least one dose of documented-antibacterial that active to the pathogen.
Exclusion criteria
Exclusion criteria: Infected pathogen which resistant to carbapenems excepted Proteus app., Providencia app., or M. morganii that resistant to imipenem only. Children who admit less than 48 hours after infected time. Clinical symptoms or laboratory diagnosis did not match diagnosis criteria. Cannot evaluate clinical outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality rate 30 days after infection time percent | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment failure rate 30 days after infection time percent | — |
Countries
Thailand
Contacts
Public ContactWatsa Charoenwaiyachet
Faculty of Pharmaceutical Sciences, Chulalongkorn University
Outcome results
None listed