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Association between Sarcopenia and Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Association between Sarcopenia and Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20220405005
Enrollment
641
Registered
2022-04-05
Start date
2021-03-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-alcoholic fatty liver disease (NAFLD) is becoming more common in the general population around the world, especially in Asia. Sarcopenia is a condition characterized by a loss of muscle mass, strength, and function that occurs over time. Several studies have reported that sarcopenia is associated with nonalcoholic fatty liver disease in the general population. However, studies have investigated the association between sarcopenia and NAFLD in individuals with Type 2 diabetes mellitus (T2DM) i

Interventions

The presence of low muscle mass and function were used to diagnose sarcopenia. TANITA BC-420 was used to obtain bioelectrical impedance (BIA). Skeletal muscle mass/height2 of less than 7 kg/m2 in male
Other,Other

Sponsors

Thai Association for the Study of the Liver (THASL)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age more than 18 years old with type 2 diabetes mellitus from the outpatient clinic at Siriraj hospital

Exclusion criteria

Exclusion criteria: Patients with viral hepatitis, alcoholic liver disease, metabolic liver disease, autoimmune liver disease, and hepatocellular carcinoma Patients with pregnancy Patients with significant alcohol consumption Patients with malignancy Patients with disability

Design outcomes

Primary

MeasureTime frame
Presence of NAFLD at time of investigation CAP

Secondary

MeasureTime frame
Severity of NAFLD at time of investigation TE, FAST score

Countries

Thailand

Contacts

Public ContactThitipon Chanjanakitskul

Siriraj hospital

thitiponch@hotmail.com0867769276

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026