Heathy person Chloasma, Facial hyperpigmentation, Pigmentary disorder, Postinflammatory hyperpigmentation
Conditions
Interventions
One side was randomly treated with alexandrite 755-nm picosecond laser ,One side was randomly treated with Nd:YAG 1064-nm picosecond laser
Experimental Device,Active Comparator Device
alexandrite 755-nm picosecond laser ,Nd:YAG 1064-nm picosecond laser
Sponsors
Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Healthy subjects older than 18-year-old
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: (i) severe medical conditions, (ii) other skin diseases on the face, (iii) immunocompromised status, (iv) history of skin cancer or keloids, (v) history of recurrent herpes infection, (vi) coagulopathy, (vii) history of laser/light therapy or other facial procedures at cheek within 2 months prior to the study, (viii) history of chemical peeling for melasma within 2 months prior to the study, (ix) history of topical treatment for melasma within 1 month prior to the study, and/or (x) pregnant or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative lightness index 4 and 8 weeks after completing the 5th treatment sessions colorimeter | — |
Secondary
| Measure | Time frame |
|---|---|
| Melasma Area and Severity Index (MASI) 4 and 8 weeks after completing the 5th treatment sessions physician (blinded) | — |
Countries
Thailand
Contacts
Public ContactVasanop Vachiramon
Faculty of Medicine, Ramathibodi hospital
Outcome results
None listed