Oblique Lumbar Interbody Fusion Minimal Invasive Transformational Lumbar Inter-body Fusion surgery MIS TLIF OLIF Spine surgery Epidural Stress response cytokines inflammatory cytokine IL-6 IL-1 postoperative pain length of stay
Conditions
Interventions
single shot epidural anesthesia, Touchy N.18, paramedian approach
level T10-11 or T11-12, loss of resistance by air
drug - 0.25% bupivacaine 10 ml with morphine 4 mg,Standard general anesthesia car
Experimental Procedure/Surgery,No Intervention Procedure/Surgery
Combined Epidural anesthesia and general anesthesia ,General anesthesia
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. age 18-80 year 2. ASA physical status I-III 3. have an indication for laminectomy+/- fusion 1-3 levels as elective surgery
Exclusion criteria
Exclusion criteria: 1. contraindication to epidural anesthesia 2. deny epidural anesthesia 3. cannot cooperate 4. allergy to any drug which used in this research 5. GFR < 30 ml/min/1.73 m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| level of inflammatory cytokines (IL1,IL6) 24hour after surgery Laboratory assessment via blood sample | — |
Secondary
| Measure | Time frame |
|---|---|
| amount of pain medication needed within 5 day after surgery Data collection,Pain within 5 day after surgery visual analogue score,Length of hospital stay until discharge from hospital Data collection | — |
Countries
Thailand
Contacts
Public ContactMarvin Thepsopan
Anesthesiology department
Outcome results
None listed