Effects of a grape seed oil (Vitis vinifera L.) loaded dermocosmetic nanoemulgel on biophysical parameters of facial skin

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220314003

Enrollment

Registered

2022-03-14

Start date

2021-10-14

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Skin color Erythema Sebum Moisture Elasticity Pores Nanoemulgel Emulgel Human skin Skin color

Interventions

The effects of a nanoemulgel loaded with grape seed oil on the biophysical parameters of facial skin are being compared to those of the control (base without grape seed oil)

Placebo Comparator Other

Nanoemulgel loaded with grape seed oil

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1) Being 18 years and older, 2) having a Fitzpatrick skin phototype III, 3) absence of facial and/or forearm skin abnormalities, 4) expressing willingness to participate in the study, 5) willingness to refrain from applying other facial cosmetics during the study period, and 5) providing written informed consent

Exclusion criteria

Exclusion criteria: Pregnancy, breastfeeding, signs/history of allergy/hypersensitivity, use of photosensitizing medications, and/or signs/history of skin diseases

Design outcomes

Primary

Measure	Time frame
Skin melanin level 12 weeks Mexameter	—

Secondary

Measure	Time frame
Skin erythema 12 weeks Mexameter	—

Countries

Palestine

Contacts

Public ContactHassan Fitian

An-Najah National University

irb@najah.edu0097092345115

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026