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The effect of tadalafil in the treatment of erectile dysfunction in patients with chronic renal failure

Comparison of the efficacy of tadalafil in the treatment of erectile dysfunction of patients under hemodialysis or kidney transplants

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220310008
Enrollment
45
Registered
2022-03-10
Start date
2022-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

erectile dysfunction end stage renal disease haemodialysis kidney transplant Erectile Dysfunction Kidney Failure, Chronic Renal Dialysis Kidney Transplantation

Interventions

End-stage renal disease patients undergoing haemodialysis receive 5 mg of tadalafil every three days and are evaluated every 2 to 4 weeks.,End-stage renal disease patients who underwent unilateral kid
Active Comparator Drug,Active Comparator Drug,Active Comparator Drug
Haemodialysis,First time kidney transplantation,non-First time kidney transplantation

Sponsors

Urology-Nephrology Research Center of Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. End stage renal disease with any kind of renal replacement therapy (haemodialysis or kidney transplantation), 2. Erectile dysfunction

Exclusion criteria

Exclusion criteria: 1. Cognitive impairment, 2. Communication impairment, 3. Genital anatomical deformity, 4. Time from last transplant of less than 6 months, 5. Taking drugs causing erectile dysfunction (e.g. beta-blockers, tricyclic antidepressants), 6. Taking nitrate derivatives and nitric oxide donors, 7. Not prepared to discontinue other erectile dysfunction treatments in the coarse of the study

Design outcomes

Primary

MeasureTime frame
Erectile Function at 4 weeks of initiating medication consumption International Index of Erectile Function 15 score

Secondary

MeasureTime frame
Headache at 4 weeks of initiating medication consumption Pain scale chart

Countries

Iran

Contacts

Public ContactMehdi Dehghani

Urology-Nephrology Research Center

info@unrc.ir22567222

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026