The study will perform on healthy human volunteers. prolonged sitting, vascular function
Conditions
Interventions
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: The participants will be recruited if they are healthy sedentary men and women who are desk-based office workers aged between 18-35 years will be recruited. All participants work at least 35 hours per week and report sitting for a minimum of 75% of their normal workday. All participants engage in less than 60 minutes of moderate to vigorous-intensity physical activity per week. Because fluctuations in estrogen can affect cardiovascular measurements, women will be reported for outcome measurements in the early follicular phase. Women reporting contraceptive use will be tested during the placebo week.
Exclusion criteria
Exclusion criteria: Exclusion criteria include the following: any history or symptom of CVDs, pulmonary, metabolic, or neurological disease, BMI over 30 kg/m2, pregnant women, taking medication that may influence vascular function, and smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vacular parameters The vascular parameters will be measure at pre-test and 8-week of intervention. Brachial-Ankle Pulse wave velocity, Flow-mediated dilation | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood chemistry The blood chemistry will be measure at pre-test and 8-week of intervention. fasting blood sugar, total choresterol, triglycerides | — |
Countries
Thailand
Contacts
Mahidol University