patients who expressed dissatisfaction with their nasolabial folds based on a score of -1 or -2 on the Subject Wrinkle Assessment Scale Nasolabial fold
Conditions
Interventions
Each patient from the autologous fibroblast group had their tissue collected at the post-auricular area. Preoperatively, 2 percent lidocaine was injected and a 3-mm punch biopsy was performed. The don
Q-Med, Uppsala, Sweden) on both NLFs (0.5 ml each side).
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Autologous fibroblast,Hyaluronic acid filler
Sponsors
Research department, Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: patients who expressed dissatisfaction with their nasolabial folds based on a score of -1 or -2 on the Subject Wrinkle Assessment Scale
Exclusion criteria
Exclusion criteria: (1) were pregnant or lactating; (2) had a history of connective tissue disorder, skin cancers, or related diseases; (3) had previous autologous fibroblast treatment; (4) had previous treatment with fillers, lasers or energy-based devices within the last 12 months; (5) had previous treatment using transdermal drug delivery, chemical peeling or topical retinoid within the last month; or (6) had allergy to collagen, meat and dairy products, gentamycin, amphotericin B, or related products.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical improvement 1-, 3-, 6-, and 12-months follow-up increation of facial volume captured by Vectra H1 Imaging System | — |
Secondary
| Measure | Time frame |
|---|---|
| safety 1-, 3-, 6-, and 12-months follow-up history taking and physical examination | — |
Countries
Thailand
Contacts
Public ContactRungsima Wanitphakdeedecha
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed