Healthy female volunteers age between 20-55 years old Skin hydration, wrinkles, skin elasticity, skin lightening, Transepidermal water loss
Conditions
Interventions
Treatment at facial skin for 8 weeks [ before treatment with the product [baseline]],
2 week,
4 week,
6 week and 8 week]
Experimental Other
THE TREATMENT SERUM
Sponsors
Mr. Jirasit Inthorn, Pibulsongkram Rajabhat University
Eligibility
Sex/Gender
Female
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Healthy female age between 20-55 years old 2. All skin types 3. Having clearly visible wrinkle at eye corner [ crow's feet] or forehead 4. Having Fitzpatrick skin type II-V 5. Having experience using a counter brand facial skin care 6. No wound, scar or any dermatological disorder on face 7. No smoking, alcoholic drinking or addiction to any narcotic substances history 8. No allergic history to any ingredient in commercially available anti-wrinkle products or cosmetics in the market 9. Willing to participate in the study after being informed objective, methodology, possible risk and result, and be able to follow the study protocol during the 8-week study period 10. Be able to read, communicate and write Thai language
Exclusion criteria
Exclusion criteria: 1. Having a history of hyperallergic reaction 2. Having a history of skin eczema psoriasis within 6 months before enter the study 3. Having a history of using steroid antibiotic NSAIDs and antihistamine within 3 days before enter the study 4. Having a history of using any topical medicine on the face in the last 3 weeks before enter the study 5. Having underlying disease and continuous taking or applying medicine for facial treatment 6. History of major operation within 1 year 7. History of skin cancer within 1 year 8. Having pregnancy or lactation 9. Having wound and scar around study-evaluating face area 10. Having history of participating in other clinical study within 3 months before enrollment in this study 11. Having allergic history of rice or rice extract cosmetic product
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin moisture 8 weeks Corneometer,Skin roughness and wrinkles 8 weeks Primos,Skin elasticity 8 weeks Cutometer,Skin lightening effect 8 weeks Mexameter,Transepidermal Water Loss 8 weeks Tewameter, Crow's feet area. 8 weeks Digital photograph [ Canon EOS Rebel T5i 700D] | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactNeti Waranuch
Cosmetics and natural products research center, faculty of Pharmaceutical sciences, NU
Outcome results
None listed