Healthy volunteers age between 30-50 years old Wrinkles, skin moisture
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female between the age 30 and 50 years old 2. All skin types [ normal, dry, oily and combination skin] 3. Having clearly visible wrinkle at eye corner [ crow's feet] or forehead 4. Having experience using a counter brand facial skin care 5. No allergic history to any ingredient in commercially available anti-wrinkle product 6. No history of changing any facial skin care product or dietary supplement within 1 month before entrollment in this study
Exclusion criteria
Exclusion criteria: 1. Having a history of skin eczema psoriasis within 6 months before enter the study 2. History of major operation within 1 year 3. History of skin cancer within 1 year 4. Having wound and scar around study-evaluating face area 5. Having history of using steriod, antibiotic, non-steriod anti-inflammatory or antihistamine within 3 days before enrollment in this study 6. Having underlying disease and continuous taking or applying medicine for facial treatment 7. Pregnancy or lactation 8. Heavy smoker or regular drinker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin roughness, Skin moisture and Visible photograph 8 weeks PRIMOS, CORNEOMETER and digital photograph | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, faculty of Pharmaceutical sciences, NU