postmenopausal women genistein postmenopause skin
Conditions
Interventions
Apply 0.6 ml on face skin twice daily in the morning and evening,Apply 0.6 ml on face skin twice daily in the morning and evening
Genistein nutraceutical products,Placebo
Sponsors
Faculty of Medicine, Chiang Mai University
Eligibility
Sex/Gender
Female
Age
48 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Healthy postmenopausal woman aged 48-65 years who has no menstruation for at least 12 months, be able to read and write in Thai, and be able to give consent by herself 2. Blood FSH >30 mU/ml 3. Body mass index = 18-30 kg/m2 4. CBC, AST, ALT, ALP, BUN, creatinine, and electrolytes show no clinically significance
Exclusion criteria
Exclusion criteria: 1. Estrogen or isoflavone treatment within 6 months prior to the study 2. Having allergic history to soy products, vitamin E, vitamin B3 or ceramide 3. Having medical history including skin cancers or skin infections or chronic diseases that contraindicated to soy products 4. Receiving medications, dietary supplement, herbal products, vitamin or minerals, or any products that may affect to skin such as antibiotics, steroid, immunosuppressants within 3 months prior to the study 5. Drinking alcohol, smoking or using recreational or narcotic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin measurement 0, 3, and 6 weeks Non-invasive instrument | — |
Secondary
| Measure | Time frame |
|---|---|
| Satisfaction 3 and 6 weeks Satisfaction | — |
Countries
Thailand
Contacts
Public ContactMingkwan Na Takuathung
Deparment of Pharmacology, Faculty of Medicine, Chiang Mai University
Outcome results
None listed