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Gummy Lactobacillus plantarum Dad-13 modulates gut microbiota in moderate undernutrition infants

Gut Microbiota Modulation of Moderate Undernutrition in In-fants through Gummy Lactobacillus plantarum Dad-13 Consumption: A Randomized Double-Blind Controlled Trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220209009
Enrollment
40
Registered
2022-02-09
Start date
2020-01-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moderate undernutrition moderate undernutrition L. plantarum Dad-13 gut microbiota

Interventions

The subjects are asked to consume gummy containing L. plantarum Dad-13 (108-9 CFU/3 g) once a day. The main ingredients of gummy consist of bovine gelatin, sucrose, glucose, water, and skim milk cont
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
probiotic ,placebo

Sponsors

Ministry of Research and Technology/National Research and Innovation Agency of Republic Indonesia (RISTEK-BRIN)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
24 Months to 60 Months

Inclusion criteria

Inclusion criteria: 1. Z score cut off between -2 and -3 standard deviation 2. not consuming probiotics, prebiotics, or antibiotics a month before the study

Exclusion criteria

Exclusion criteria: 1. refuse to consume research product 2. consume other probiotic products 3. consume antibiotic and laxative

Design outcomes

Primary

MeasureTime frame
Anthropometry before-after body weight and body height,Gut microbiota composition before-after gut microbiota taxonomy and absolute number of specific bacteria

Secondary

MeasureTime frame
Dietary intake during intervention period macro and micro nutrient intake ,SCFA before-after SCFA concentration (Total SCFA, acetic, propionic, and butyric acid),stool pH before-after stool pH

Countries

Indonesia

Contacts

Public ContactEndang Rahayu

Centre for Food and Nutrition Studies

endangsrahayu@ugm.ac.id8122690013

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026