Mild cognitive impairment memory function thai traditional herbal medicine kleeb bua daeng
Conditions
Interventions
two capsules twice a day,two capsules twice a day
Experimental Drug,Placebo Comparator Drug
Kleeb Bua Daeng capsule,Placebo
Sponsors
Chao Phya Abhaibhubejhr Hospital Foundation
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: MCI patients in Chao Phya Abhaibhubejhr hospital, Prachinburi of Thailand, were enrolled. The inclusion criteria were as follows: Provision of signed informed consent before any study-specific procedure, MoCA (Montreal Cognitive Assesssment)-T score between 19-24, and 40-70 years of age.
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: GFR by Cockcroft formulation less than 40 ml/min, serum alanine aminotransferase and aspartate aminotransferase higher than 2.5 of standard level, patients who receive warfarin, pregnancy or breastfeeding, need for or an anticipated need for oral with any of the following: (a) Cholinesterase inhibitors (b) N-methyl D-aspartate antagonist (NMDA) (c) Cholinesterase inhibitors plus NMDA, and participation in another clinical study with an investigational product at any time during the 30 days before randomization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AST at 3 month ast level,ALT at 3 month alt level,MoCA at 3 month MoCA score,eGFR at 3 month eGFR level | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse event at 3 month number of event | — |
Countries
Thailand
Contacts
Public ContactNatdanai Musigavong
Khon Kaen university
Outcome results
None listed