Psoriasis patients with mild to moderate severity Psoriasis, Cannabidiols, CBD
Conditions
Interventions
Psoriasis patients with CBD as an adjuvant (Active group),Psoriasis patients without CBD as an adjuvant (Control group)
Treatment,Treatment
Psoriasis patients with CBD (Active),Psoriasis patients without CBD (Control)
Sponsors
Faculty of Medicine, Western University
National Research Council of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. A patient who has been diagnosed with psoriasis, treated in the outpatient department of Nawamin Hospital, aged 18 years and over, both male and female. 2. Psoriasis patient group with mild disease severity (PASI score less than 3) or psoriasis patients with moderate disease severity (PASI score 3-10) 70 patients 3. BSA value less than 90 4. No complications from other diseases such as severe skin infections. No psoriatic arthritis conditions, cardiovascular disease. 5. Patients with normal LFT, AST (SGOT) and ALT (SGPT) not more than 2 times normal. 6. RFT eGFR value more than 59 7. Able to speak, read, listen and understand Thai language 8. Willing to cooperate/voluntarily join the trial along with signing a written consent to participate in the research project
Exclusion criteria
Exclusion criteria: 1. Psoriasis patient group with a high degree of disease severity (PASI score more than 10) 2. BSA value more than 90 or increased by more than 2 times during treatment 3. LFT AST (SGOT), ALT (SGPT) greater than 2 times normal during treatment 4. RFT eGFR less than 59 (Stage 3a) during treatment. 5. Having complications from other diseases such as severe skin infections No psoriatic arthritis conditions, cardiovascular disease. 6. Patients who need to use group drugs Beta-Blockers and Oral Steroids or a history of medicinal cannabis use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Responder rate 3-6 months PASI score | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life 3-6 months PGI-B, PGI-C, PBI-S, MOS SF12 | — |
Countries
Thailand
Contacts
Public ContactPornthep Siriwanarangsan
Faculty of Medicine, Western University
Outcome results
None listed