Ethambutol optic neuropathy Ethambutol, optic neuropathy, tuberculosis, risk factor, incidence, clinical
Conditions
Interventions
patient with Ethambutol optic neuropathh,Patient who receive Ethambutol but no optic neuropathy found.
Other,Other
EON,control
Sponsors
Rajavithi Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patients who received ethambutol for TB treatment at Rajavithi Hospital, Bangkok, Thailand from January 2012 to August 2019. 2. The patients who had decreased vision after ethambutol treatment and were diagnosed as ethambutol-induced optic neuropathy (EON) by experienced neuro-ophthalmologists were included as EON group. 3. The patients who received ethambutol during the study period without visual symptoms were included as Control group.
Exclusion criteria
Exclusion criteria: 1. EON patients with other ophthalmic conditions resulting in significant visual obscuration such as retinal and macular diseases, cataract, diabetic retinopathy, glaucoma, or other optic neuropathies were excluded. 2. The patients who had incomplete or lost medical record.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence, risk factor, clinical n/a number and opd record | — |
Secondary
| Measure | Time frame |
|---|---|
| ophthalmic investigation result n/a ophthalmic investigation machine | — |
Countries
Thailand
Contacts
Public ContactPareena Chaitanuwong
Rajavithi Hospital
Outcome results
None listed