Booster vaccination with mRNA 1273 COVID vaccine in individuals who had received 2 doses of CoronaVac and booster with BNT162b2 or ChAdOx-1 COVID vaccine. mRNA 1273 , booster, covid 19 vaccine, immunogenicity
Conditions
Interventions
An adults aged 18 years and older who had received 2 doses of CoronaVac and booster with ChAdOx-1 vaccine.,An adults aged 18 years and older who had received 2 doses of CoronaVac and booster with BNT1
Basic Science,Basic Science
Sponsors
Thammasat University Hospital
No Study Secondary Sponsor
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: A healthy adults aged 18 years and older who had received 2 doses of CoronaVac and booster with BNT162b2 or ChAdOx-1 COVID vaccine.
Exclusion criteria
Exclusion criteria: - Acute fever with body temperature above 38 degree Celsius on the day of vaccination. - History of COVID-19 infection - Get another vaccination no more than 2 weeks before enrollment. - pregnant with a gestational age of less than 12 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunogenicity 14 days after complete vaccination Anti-S-RBD antibody level ,Reactogenicity 7 days after vaccination Diary card | — |
Secondary
| Measure | Time frame |
|---|---|
| Persistent of immune response 6 months after complete vaccination Anti-S-RBD antibody level and ELISpot,Immunogenicity 6 months after complete vaccination Anti-S-RBD antibody level and ELISpot | — |
Countries
Thailand
Contacts
Public ContactAuchara Tangsathapornpong
Faculty of Medicine, Thammasat University
Outcome results
None listed