Irritation studies were conducted in healthy participants. therefore, Healthy participants had no complications in this study. Irritation, Skin test
Conditions
Interventions
Natural fibers from pineapple fibers are coated with polyacrylic acid combined with chlorhexidine by fluidization coating technique.
Experimental Device
Irritation study of Medical absorbent pad from pineapple fibers coat with polyacrylic acid and chlorhexidine
Sponsors
Government Pharmaceutical Organization
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Healthy volunteers 2. Male and female Aged between 18-50 years 3. Interview volunteers before starting the research study. The subjects had no history of allergy to chlorhexidine, such as products containing chlorhexidine in mouthwash, toothpaste, soap, cream, or a solution applied to the skin as a disinfectant. by the nature of allergic reactions such as hives, itchy rash, red swelling, difficulty breathing, swollen face, swollen lips, etc. 4. Voluntarily participate in the project after hearing a description of the research process until it is understood. and is not in the process of participating in another research project
Exclusion criteria
Exclusion criteria: 1. have a skin rash Skin disease or allergic rash is a skin lesion on the back. 2. have a history of liver disease, kidney disease, blood disease or other serious disease that will affect the test 3. Taking or applying immunosuppressants or corticosteroids or other immunosuppressive drugs during the test. and did not stop taking the drug at least 2 weeks before the test 4. Pregnant women or women who wish to conceive during the research period including women who are breastfeeding 5. Have a history of allergy or allergic to plaster, micropore/microfilm. 6. Never stop applying skin care products. At least 1 week before the test 7. Volunteers with a history of allergy to rubber, banana, avocado, kiwi and pineapple.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| irritant 1 month after intervention Grading for irritant patch test | — |
Secondary
| Measure | Time frame |
|---|---|
| number of Irritation cases 1 month after intervention irritation cases reported outcome using physician | — |
Countries
Thailand
Contacts
Public ContactKomgrit Eawsakul
School of medicine, Walailak University
Outcome results
None listed