sick sinus syndrome patients with pre-existing bundle branch block and preserve left ventricular systolic function sick sinus syndrome, bundle branch block, left bundle branch area pacing, dual chamber pacemaker, electrocardiography, echocardiogram
Conditions
Interventions
All patients in the study undergo dual-chamber pacemaker (Medtronic Inc., Minneapolis, MN, USA) implantation. The right atrial lead is connected to the atrial port. LBBAP is achieved using a transvent
Experimental Device
Sponsors
Research Funds, Faculty of Medicine, Khon Kaen Universit
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged 18-80 years 2. Patients with SSS who meet indications for pacemaker implantation 3. ECG showed preexisting BBB 4. Ability to provide informed consent
Exclusion criteria
Exclusion criteria: 1. Requirement of ventricular pacing 2. LVEF less than 50% 3. Failure to cooperate with follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QRS pattern and duration 3 months electrocardiography (ECG),septal-to-posterior wall motion delay 3 months millisecond (measured by echocardiogram),longitudinal color tissue Doppler velocity 3 month millisecond (measured by echocardiogram),interventricular mechanical delay 3 months millisecond (measured by echocardiogram) | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-proBNP 3 months pg/mL,LVEDD 3 months mm (measured by echocardiogram),E/E' 3 months echocardiogram | — |
Countries
Thailand
Contacts
Public ContactPeerawat Sukkul
Faculty of Medicine, Khon Kaen University
Outcome results
None listed