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A Comparison of Hearing Level between Before and After Intratympanic Dexamethasone Injection in Patient with Sudden Sensorineural Hearing Loss after Failure of Oral Prednisolone Therapy

A Comparison of Hearing Level between Before and After Intratympanic Dexamethasone Injection in Patient with Sudden Sensorineural Hearing Loss after Failure of Oral Prednisolone Therapy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220128003
Enrollment
35
Registered
2022-01-28
Start date
2020-02-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intratympanic Dexamethasone Injection in Patient with Sudden Sensorineural Hearing Loss after Failure of Oral Prednisolone Therapy Idiopathic sudden sensorineural hearing loss Intratympanic dexamethasone injection ineffective oral prednisolone

Interventions

Materials and methods: quasi-experimental study, Prospective data were collected in 40 sudden sensorineural hearing loss patients treated with ineffective oral prednisolone. Dexamethasone were then in
Experimental Procedure/Surgery

Sponsors

Chaophrayayommarat Hospital Ethical Committee
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Over 18 years of age, having a hearing level greater than 30 decibels over 3 consecutive frequencies. by the time since the disease until less than 4 weeks, did not respond to treatment with oral prednisolone

Exclusion criteria

Exclusion criteria: Otitis, eardrum perforation, ear infection, history of head injury, history of surgery or an ear accident or have had radiation to the head and neck, received steroids by mouth or injection within 1 month before diagnosis, allergic to steroids or anesthetics, water in the ear, History of meningitis

Design outcomes

Primary

MeasureTime frame
Pure tone Audiogram level 1 month Decibel

Secondary

MeasureTime frame
Speech discrimination score 1 month percent

Countries

Thailand

Contacts

Public Contactwuttiwet Jaratmanachote

Chaoprayayommarat hospital

wuttiwechjarat@gmail.com0846167732

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026