Feasibility and safety of treating malunion distal end radius, corrective osteotomy with bone marrow-derived mesenchymal stem cells and Hydroxyapatite: Translational study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220124001

Enrollment

Registered

2022-01-24

Start date

2022-01-19

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malunion distal end radius Malunion distal end radius Corrective osteotomy Volar locking plate distal end radius Mesenchymal stem cell Bone graft

Interventions

At time of corrective osteotomy distal end radius, bone marrow of patient was took for culture mesenchymal stem cell and synthetic bone graft was took at osteotomy site. At 3 weeks post operatively cu

Experimental Biological/Vaccine

Mesenchymal stem cell injection and HA

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Malunion Distal end radius with radial inclination less than 15 degree or dorsal tilt more than 10 degree or ulnar variance more than 3 mm

Exclusion criteria

Exclusion criteria: Other bone fracture or deformity Patient with underlying disease Pregnant or breastfeeding patient

Design outcomes

Primary

Measure	Time frame
Feasibility and safety 6 month after intervention no complication	—

Secondary

Measure	Time frame
Bone union time 3 month Bone union time	—

Countries

Thailand

Contacts

Public ContactThanat Charoenpol

Faculty of Medicine Ramathibodi Hospital, Mahidol University

thanat_charoenpol@hotmail.com0894980808

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026