The number of candida growth Candida Species S-PRG filler Nano-sized S-PRG filler Micro-sized S-PRG filler Candida albicans Candida tropicalis Resin Denture Base
Conditions
Interventions
PMMA resin containing 0wt% S-PRG ,PMMA resin containing 10 wt% S-PRG nanofiller ,PMMA resin containing 20 wt% S-PRG microfiller
Placebo Comparator Biological/Vaccine,Experimental Biological/Vaccine,Experimental Biological/Vaccine
0wt%S-PRG ,10 wt% S-PRG nanofiller,20 wt% S-PRG microfiller
Sponsors
Faculty of dentistry, Thammasat university
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Thai patients, age between 50-80year, 2.Healthy, 3.ability to perform basic self-care, 4.having full edentulous ridges, 5.Unstimulated whole saliva more than or equal to 0.5 ml/min.
Exclusion criteria
Exclusion criteria: 1.Disability patients, 2.unstimulated saliva flow rate less than0.5 ml/min, 3. Allergy to denture resin, 4. Immunocompromised patient, 5. Received antibiotic therapy, 6.having denture stomatitis, 7. receiving medication or having medical conditions that predispose or promote to oral candidiasis such as uncontrolled diabetes mellitus, anemia or immunodeficiency disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effectiveness of a modified resin denture base containing S-PRG microfillers and nanofillers in inhibiting candida growth among healthy Thai elderly individuals wearing complete dentures. Baseline (At the delivery visit), after wearing the denture for 1 month and 3 months Samples were collected using an oral rinse technique and examine the number of candida growth and identified candida species with MALDI-TOF MS. | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactSakulthip Saichompoo
Faculty of dentistry, Thammasat university
Outcome results
None listed