Comparative efficacy study of dexamethasone and placebo in pain control after anterior cervical discectomy and fusion with anterior plate fixation; A randomized trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220117006

Enrollment

Registered

2022-01-17

Start date

2022-01-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-operative pain control after anterior cervical discectomy and fusion with anterior plate fixation pain dexamethasone ACDF anterior cervical discectomy and fusion with anterior plate fixation morphine consumption

Interventions

dexamethasone 0.2 mg/kg intravenous route,normal saline 2 ml intravenous route

Placebo Comparator Drug,Placebo Comparator Drug

dexamethasone,placebo

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: admit for anterior cervical discectomy and fusion with anterior plate fixation, not excess 3 level, with Polyetheretherketone, PEEK) no morphine consumption within 180 day prior to surgery age above 18 years old

Exclusion criteria

Exclusion criteria: previos cervical spine surgery active smoking within 6 months need dexamethasone for treatment in other medical condition contraindication for dexamethasone

Design outcomes

Primary

Measure	Time frame
morphine consumption 48 hours observe	—

Secondary

Measure	Time frame
pain scale 48 hours questionnaire	—

Countries

Thailand

Contacts

Public ContactBhattharamon Chaisombat

Khon Kaen university

Bhattharamon.c@kkumail.com66842795590

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026