Skip to content

A randomized comparison of the effects of budesonide spray and K-Y gel as an endotracheal tube cuff lubricant on the incidence of postoperative sore throat

A randomized comparison of the effects of budesonide spray and K-Y gel as an endotracheal tube cuff lubricant on the incidence of postoperative sore throat

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20220113001
Enrollment
100
Registered
2022-01-13
Start date
2019-01-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sore throat (POST) is a frequent complication following tracheal intubation under general anesthesia. postoperative sore throat, cough, hoarseness, budesonide spray, intubation

Interventions

In the budesonide group 200 mcg of budesonide was sprayed on the cuff of the endotracheal tube 10 minutes before tracheal intubation,For the control group K-Y gel was lubricated on the entire endotra
Experimental Drug,No Intervention No treatment
budesonide group ,control

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: aged 18 to 60 years old with the American Society of Anesthesiologists (ASA) physical status 1-2 and Mallampati score 1-2 who were undergoing elective non-cardiac surgery under general anesthesia with an endotracheal tube

Exclusion criteria

Exclusion criteria: Patients with an expected difficult airway, those who required more than two attempts at intubation, and those with a pre-operative sore throat, a history of allergy to budesonide, and nonsteroidal anti-inflammatory drugs (NSAIDs)

Design outcomes

Primary

MeasureTime frame
incidence of POST at 2, 6, and 24 hours after surgery Number of event

Secondary

MeasureTime frame
severity of POST at 2, 6, and 24 hours after surgery visual analog scale ,the adverse effects of budesonide during surgery to 24 hours after surgery Number of event,hoarseness and cough at 2, 6, and 24 hours after surgery number of event

Countries

Thailand

Contacts

Public Contactkantarakorn unchiti

chiangMai university

kantarakorn.u@gmail.com0899556664

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026