Postoperative analgesic efficacy of IPACK block or genicular nerve block as an adjunct to proximal femoral triangle block for arthroscopic anterior cruciate ligament reconstruction

Status

Unknown

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20220112003

Enrollment

Registered

2022-01-12

Start date

2022-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthroscopic anterior cruciate ligament reconstruction IPACK block Genicular nerve block Postoperative pain Anterior Cruciate Ligament Reconstruction Nerve Block Postoperative Pain

Interventions

Infiltration between the popliteal artery and the capsule of the knee,Infiltration around the sensory branches of the knee joint

Experimental Procedure/Surgery,Experimental Procedure/Surgery

IPACK block,GN block

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Elective unilateral ACLR BMI 18-40 kg/m2 ASA class I-III

Exclusion criteria

Exclusion criteria: Previous knee surgery Chronic knee pain Chronic opioid drug use Preexisting femoral nerve deficit or peripheral neuropathy Allergic to drugs used in this study Contraindication of peripheral nerve block (e.g., coagulopathy, infection at block site) Co-injury of the structures in the knee (meniscal injury, cartilage injury, bone fracture, multiple ligament injury)

Design outcomes

Primary

Measure	Time frame
Morphine consumption within 24 hours after a nerve block procedure A total morphine dose (mg) that a patient receives after surgery,Time to first morphine use within 24 hours after a nerve block procedure Time (minutes) from a nerve block procedure to 1st morphine request,Postoperative resting and dynamic pain every 4 hours within 24 hours after a nerve block procedure Numeric rating score of knee pain at rest and with motion reported by a patient,Incidence and severity of posterior knee pain within 48 hours after a nerve block procedure Incidence and severity of pain at posterior aspect of the knee	—

Measure

Time frame

Morphine consumption within 24 hours after a nerve block procedure A total morphine dose (mg) that a patient receives after surgery,Time to first morphine use within 24 hours after a nerve block procedure Time (minutes) from a nerve block procedure to 1st morphine request,Postoperative resting and dynamic pain every 4 hours within 24 hours after a nerve block procedure Numeric rating score of knee pain at rest and with motion reported by a patient,Incidence and severity of posterior knee pain within 48 hours after a nerve block procedure Incidence and severity of pain at posterior aspect of the knee

—

Secondary

Measure	Time frame
Intraoperative fentanyl consumption During surgery A total fentanyl dose (mcg) that a patient receives during surgery,Time readiness to be discharged from postanesthesia care unit within 3 hours after surgery Time period (minutes) from PACU arrival to Modified Aldrete score higher than or equal to 9,Motor weakness after a nerve block procedure within 30 minutes after a nerve block procedure Difference between baseline and post-procederal strength of quadiceps muscle, ankle plantar flexion and dorsiflexion,Incidence of postoperative motor weakness during physical therapy within 48 hours after a nerve block procedure Difference between baseline and post operative degree quadricep muscle strength (Q-lag) during physical therapy,Length of hospital stay within 7 days after surgery Time period (days) from admission to discharge,Patient satisfaction to analgesia technique within 48 hours after surgery 11-point Likert scale,Incidence of adverse events of nerve block within 48 hours after surgery incidence of vascular puncture, paresthesia, LA toxicity, allergic reaction, infection, bleeding at injection site	—

Measure

Time frame

Intraoperative fentanyl consumption During surgery A total fentanyl dose (mcg) that a patient receives during surgery,Time readiness to be discharged from postanesthesia care unit within 3 hours after surgery Time period (minutes) from PACU arrival to Modified Aldrete score higher than or equal to 9,Motor weakness after a nerve block procedure within 30 minutes after a nerve block procedure Difference between baseline and post-procederal strength of quadiceps muscle, ankle plantar flexion and dorsiflexion,Incidence of postoperative motor weakness during physical therapy within 48 hours after a nerve block procedure Difference between baseline and post operative degree quadricep muscle strength (Q-lag) during physical therapy,Length of hospital stay within 7 days after surgery Time period (days) from admission to discharge,Patient satisfaction to analgesia technique within 48 hours after surgery 11-point Likert scale,Incidence of adverse events of nerve block within 48 hours after surgery incidence of vascular puncture, paresthesia, LA toxicity, allergic reaction, infection, bleeding at injection site

—

Countries

Thailand

Contacts

Public ContactPrangmalee Leurcharusmee

Faculty of Medicine, Chiang Mai University

prangmalee.l@cmu.ac.th6653935522

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026