dyslipidemia (high level of low-density lipoprotein cholesterol (LDL-C) in the range of 130-160 mg/dL) Clinical trial, Dyslipidemia, Lactobacillus paracasei, Probiotic, Vegetable and fruit juice
Conditions
Interventions
The placebo group of eligible participants received two bottles of blended vegetable and fruit juice with probiotic L. paracasei for 30 days treatment. The participants drank the juice 30 minutes b
Blended vegetable and fruit juice without probiotic L. paracasei ,Blended vegetable and fruit juice with probiotic L. paracasei
Sponsors
Bhumibol Adulyadej Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.The subjects were required to be aged at least 18 years., 2. The subjects had a high level of low- density lipoprotein cholesterol (LDL-C) in the range of 130-160 mg/dL according to the National Cholesterol Education Program (NCEP)., 3. The subjects never received medical treatment for dyslipidemia.
Exclusion criteria
Exclusion criteria: 1.Having family history of dyslipidemia, 2.Having gastrointestinal surgery, 3. Suffering from metabolic disorders, cardiovascular disease, thyroid disorder, kidney disease, and liver disease, 4. Having been treated with prebiotic and/or probiotic and/or nutrition supplements, 5. Taking other drugs which possibility affect the lipid metabolism, 6.Smoking and drinking alcohol during the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lipid profile and bile acid at 30 days after end of the intervention TC (mg/dL) LDL-C (mg/dL) HDL-C (mg/dL) TG (mg/dL) and BA (micromole/L) | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxidative stress enzymes at 30 days after end of the intervention CAT (unit/mL) GPx (unit/mL) SOD (unit/mL) | — |
Countries
Thailand
Contacts
Public ContactPattharaparn Siripun
Pharmaceutical Division, Bhumibol Adulyadej Hospital
Outcome results
None listed