The Effect of Supervised Rehabilitation Combined with Blood Flow Restriction Training in Athletes with Chronic Ankle Instability: A Randomized Placebo Controlled Trial

Effects of Blood Flow Restriction Training Combined with Rehabilitation Program on Neuromuscular Function and Balance in Athletes with Chronic Ankle Instability

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211223005

Enrollment

Registered

2021-12-23

Start date

2021-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

its functional benefits of conventional rehabilitation (R) combined with BFR in athletes with chronic ankle instability (CAI) remain unknown Chronic Ankle Instability, Occlusion, Hypertrophy, Y-balance, Side Hop Test

Interventions

the BFR+R group was applied with a cuff around the proximal thigh at 80% of arterial occlusion pressure in addition to conventional rehabilitation program,For the R group, participants wore the BFR cu

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery

conventional rehabilitation (R) combined with BFR ,Rehabilitation intervention

Eligibility

Sex/Gender

All

Age

18 Years to 23 Years

Inclusion criteria

Inclusion criteria: they had a history of unilateral lateral ankle sprain occurred at least 12 months prior to study enrolment, a history self- reported of giving way and/or feelings of ankle instability of the involved ankle during activities of daily living and/or sporting activities for at least 6 months, and a score less than or equal 24/30 on the Cumberland Ankle Instability Tool (CAIT)

Exclusion criteria

Exclusion criteria: a history of bilateral ankle instability and exhibit pathological joint laxity (a positive result on the talar tilt test or anterior drawer test), a history of ankle fracture, surgery of hip, knee, and ankle, and a history of the musculoskeletal disorders.

Design outcomes

Primary

Measure	Time frame
The isokinetic dynamometer baseline and at 4 week and 6 weeks after end of the intervention The isokinetic dynamometer was used to determine the APT of hip extensor, abductor, ankle dorsiflexor plantarflexor, and ankle evertor invertor muscles	—

Secondary

Measure	Time frame
The cross-sectional area (CSA) baseline and at 4 week and 6 weeks after end of the intervention The cross-sectional area (CSA) of fibularis longus muscle was measured using B-mode a diagnostic ultrasound system ,dynamic balance baseline and at 4 week and 6 weeks after end of the intervention The Y balance test (YBT) was employed for determining a dynamic balance	—

Countries

Thailand

Contacts

Public ContactPhurichaya Werasirirat

Faculty of Sports Science, Chulalongkorn University

phurich16@gmail.com0887396279

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026