Cirrhotic patients thiamine deficiency cirrhosis Thiamine deficiency
Conditions
Interventions
The patients who were diagnosed with thiamine deficiency by ETKA equal or more than 1.25 were physically examined for nystagmus, ophthalmoplegia, ataxia to evaluate Wernicke-Korsakoff syndrome and wer
Experimental Drug
Thiamine replacement
Sponsors
Research Facilitation Division, Faculty of Medicine Vajira Hospital, Navamindradhiraj University
Eligibility
Sex/Gender
All
Age
15 Years to 80 Years
Inclusion criteria
Inclusion criteria: Cirrhotic patients were diagnosed by ultrasound, computer tomography scan (CT), transient elastography above 13 kPa, magnetic resonance imaging (MRI), or by liver biopsy
Exclusion criteria
Exclusion criteria: -who were diagnosed with thiamine deficiency or use of thiamine replacement therapy before enrolling -acute illness in 2 weeks -pregnant woman -hyperthyroidism -end-stage renal disease and on renal replacement therapy -gastrointestinal tract surgery with anastomosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prevalence of thiamine deficiency between alcoholic cirrhosis and non-alcoholic cirrhosis. at diagnosis prevalence | — |
Secondary
| Measure | Time frame |
|---|---|
| factors influenced thiamine deficiency other than the etiology of cirrhosis at diagnosis data collection,clinical manifestation of thiamine deficiency patients in neurologic sign and symptom and attention deficit at diagnosis physical examination and ASRS test,improvement of thiamine deficiency after replacement 3 months 3 monts after thiamine replacement blood test and physical examination and ASRS test | — |
Countries
Thailand
Contacts
Public ContactPacharakorn Techaratanayuenyong
Bankkok
Outcome results
None listed