Healthy Thai female volunteers (30-60 years old) anti-wrinkle, Skin whitening, Skin moisture, Skin elasticity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy female between the ages of 30 and 60 2. All skin types (normal, dry, oily and combination skin) 3. Having clearly visible wrinkle at the eye corner (crow's feet) or forehead based on Wrinkle Assessment Scale 4. Having Fitzpatrick skin type II-V 5. Having experience using a counter brand facial skincare 6. Willing to participate in the study after being informed objective, methodology, risk, and benefit of the study 7. Be able to read, communicate and write Thai language
Exclusion criteria
Exclusion criteria: 1. Having a history of eczema or psoriasis within 6 months before enrollment in this study 2. Having a history of using a steroid, antibiotics, non-steroidal anti-inflammatory, or antihistamine within 3 days before enrollment in this study 3. Having a history of using topical medicine on the face within 3 weeks before enrollment in this study 4. Having underlying disease and continuous taking or applying medicine for facial treatment 5. Having a history of major operation within 1 year 6. Having a history of skin cancer within 1 year 7. Pregnancy or lactation 8. Having wound and scar around the study-evaluating face area 9. Regular smoking (defined as smoking at least 1 cigarette/day) 10. Regular drinking (defined as consuming at least 1 glass/day or 250 milliliters/day) 11. Having a history of participating in other clinical studies within 3 months before enrollment in this study 12. Having allergic history to any ingredient in commercially available anti-wrinkle products or cosmetic products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin color 4 weeks Measuring by Mexameter,Skin elasticity 4 weeks Measuring by Cutometer,Wrinkles 4 weeks Measuring by Primos,Skin moisture 4 weeks Measuring by Corneometer,Photos of wrinkles 4 weeks The photographed of wrinkles area by Omnia | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, Pharmaceutical sciences, Naresuan university