Opioid-free analgesia: Is it achievable in open colorectal surgery without neuraxial block?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20211220007

Enrollment

Registered

2021-12-20

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative consumption of opioids in open colorectal surgery opioid free analgesia multimodal analgesia postoperative pain colon rectum laparotomy

Interventions

No requirement of postoperative opioids,Requirement of postoperative opioids

Other,Other

OFA group,Non-OFA group

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult patients (aged > 18 years) undergoing elective open colectomy and/or proctectomy for benign colorectal diseases and non-metastatic colorectal adenocarcinoma (AJCC stage I-III) between January 2018 and December 2020 at the Department of Surgery, Faculty of Medicine Siriraj Hospital, Thailand.

Exclusion criteria

Exclusion criteria: Patients having an operation for recurrent tumor Patients having acute colonic obstruction or perforation Patients with American Society of Anesthesiologists physical status of IV or more Current opioid users Patients being unable to understand the concept of intravenous patient-controlled analgesia

Design outcomes

Primary

Measure	Time frame
Rate of opioid free analgesia within 30 days after an operation Amount of opioid use	—

Secondary

Measure	Time frame
30-day complication within 30 days after an operation Clavien-Dindo Classification	—

Countries

Thailand

Contacts

Public ContactVarut Lohsiriwat

Faculty of Medicine Siriraj Hospital

bolloon@hotmail.com006624198005

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026