Healthy patients undergoing operation under general anesthesia. General anesthesia.
Conditions
Interventions
Controlled group,Ephedrine 0.1 mg/kg was given to the participant before induction of anesthesia with Propofol 2.5 mg/kg and Morphine 0.1 mg/kg ,Ephedrine 0.2 mg/kg was given to the participant befor
No Intervention No treatment,Active Comparator Drug,Active Comparator Drug
Controlled,Ephedrine 0.1. mg/kg,Ephedrine 0.2 mg/kg
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: ASA PS 1-2
Exclusion criteria
Exclusion criteria: 1 Have diseases such as hypertension, cardiac/pulmonary/neurological/liver/renal/thyroid diseases 2 Allergy to drugs used in the research. 3 Taking medicines that associated to blood pressure and heart rate. 4 Difficult airway 5 Pregnancy 6 BMI > 35 kg/sq.m. 7 Risk for aspiration 8 Systolic blood pressure higher that 160 or lower that 90 mmHg before induction of anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Result of using Ephedrine for protecting hypotension from induction of anesthesia 1,2,3,4,5 minutes after induction of anesthesia Blood pressure | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate after receiving Ephedrine 1,2,3,4,5 minutes after induction of anesthesia Heart rate,Efficacy of Ephedrine in reducing hypotension 1,2,3,4,5 minutes after induction of anesthesia Blood pressure | — |
Countries
Thailand
Contacts
Public ContactPamanee Saimuey
Sakon Nakhon hospital
Outcome results
None listed