Comparing the efficacy of hemodialysis with super high-flux dialyzer between first use and repeated use

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211209004

Enrollment

Registered

2021-12-09

Start date

2021-08-30

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ESRD on regular hemodialysis Dialyzer reuse, Super high-flux dialyzer, High-performance membrane, Hemodialysis, Middle molecule uremic toxin, Beta-2 microglobulin, Total cell volume, fiber bundle volume

Interventions

Comparing between ESRD patient on regular HD with reused Elisio-21HX dialyzer and single-use Elisio-21HX dialyzer

Active Comparator Device

HD with reused Elisio-21HX dialyzer

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. ESRD on regular HD 2 with spKt/V more than 1.8 or HD 3 time/wk with spKt/V more than 1.2 2. RRF less than 100 ml/day, 3. Vascular access AVF or AVG, 4. Hemodynamic stability

Exclusion criteria

Exclusion criteria: 1. Active CVD, 2. Active malignancy, 3. Pregnancy, 4. Decompensated cirrhosis, 5. Malnutrition, 6. Patient preference

Design outcomes

Primary

Measure	Time frame
Uremic toxin 4 months Uremic toxin clearance	—

Secondary

Measure	Time frame
Dilaysate albumin 4 months gram of dialysate albumin	—

Countries

Thailand

Contacts

Public ContactPiyapun Prapunwatana

King Chulalongkorn Memorial Hospital

nut.med64@gmail.com0866642049

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026