Healthy Thai male and female aged 20-55 years skin whitening
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy male and female aged 20-55 years of all skin types (normal, dry, oily, and combination skin) 2. Having Fitzpatrick skin type III to V 3. Having clearly dark spot or uneven skin tone or dull skin 4. Be able to read, communicate and write in Thai language 5. Willing to refrain using any other whitening product and changing skin nourishing products during the study 6. Willing to participate in the project and be able to follow the study protocol 7. Willing to give a written consent after being informed the study detail
Exclusion criteria
Exclusion criteria: 1. Having wound or scar on the evaluation area of the face 2. Having history of allergy problem to any commercially available skin whitening or any counter brand cosmetic products 3. History of skin eczema, psoriasis within 6 months before entering the study 4. History of skin cancer within 1 year before entering the study 5. History of using steroid, antibiotic, NSAIDs and antihistamine within 3 days before entering the study 6. history of using topical medicine on the face within 3 weeks before entering the study 7. Having chronic diseases and continuous taking medicines 8. History of major operation within 1 year before entering the study 9. Pregnancy or lactation 10. History of daily smoking or drinking 11. Being or having experience in participating other clinical studies within the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin hydration 4 weeks Measuring by Corneometer,Skin color 4 weeks Measuring by Mexameter and Chromameter,Facial skin image 4 weeks The photographed of facial area by Omnia | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, faculty of Pharmaceutical sciences, NU