Healthy human volunteers Botulinum Toxins, Injections, Intradermal
Conditions
Interventions
Incobotulinum toxin will be injected into the face (75 units) and neck (25 units) for a total of 100 units. The injection location will be the same for every subject. Vectra3d will be used to evaluate
Sponsors
Dermatologic Surgery, Dermatology department, Siriraj hospital, Thailand
Merz Aesthetics Thailand,Galderma Thailand,Daewong Thailand,Hugel,inc
Eligibility
Sex/Gender
All
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Healthy male or female volunteers age 25-45 years, 2. No history of botulinum toxin treatment failure, 3. No history of immunodeficiency disease or taking any immunosuppressive drug, 4. Have facial sagging
Exclusion criteria
Exclusion criteria: 1. pregnant or lactating woman, 2. Was treated with botulinum toxin during 6 months prior, 3. Having the skin disease around the treated area 4. Using an energy-based device or other interventions 6 months prior
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial sagging improvement Before intervention, 14 days, 1, 2, 3, 4, 5 and 6 months after the intervention Level of improvement measure from vectra3d scan,Subject self assessment score 14 days, 1, 2, 3, 4, 5 and 6 months after the intervention percentage of Subject self assessment score,Physicians assessment score 14 days, 1, 2, 3, 4, 5 and 6 months after the intervention percentage of Physicians assessment score | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score immediate after the intervention Visual analogue scale (0-10) | — |
Countries
Thailand
Contacts
Public ContactSurachet Sirisuthivoranunt
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed