Controlling Pain after Total Knee Arthroplasty by Using Intrathecal Morphine, Peripheral Nerve Block, and Periarticular Injection.

Controlling Pain after Total Knee Arthroplasty by Using Intrathecal Morphine, Peripheral Nerve Block, and Periarticular Injection. A Propensity Score-Matched Analysis.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211207005

Enrollment

150

Registered

2021-12-07

Start date

2021-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain after total knee arthroplasty (TKA) total knee arthroplasty, postoperative pain, periarticular injection, adductor canal block, femoral nerve block, intrathecal morphine

Interventions

Patients who underwent TKA and received periarticular injection (PAI).,Patients who underwent TKA and received periarticular injection (PAI) and adductor canal block (ACB) and intrathecal morphine (IT

Active Comparator Procedure/Surgery,Experimental Procedure/Surgery,Experimental Procedure/Surgery

pai,PAI &amp

ACB * ITM,PAI &amp

FNB &amp

ITM

Eligibility

Sex/Gender

All

Age

20 Years to 90 Years

Inclusion criteria

Inclusion criteria: All patients who underwent TKA with this 3 analgesic method between 2018-2021

Exclusion criteria

Exclusion criteria: Patients who had prior knee surgery, prior knee infection will be excluded.

Design outcomes

Primary

Measure	Time frame
pain intensity 6 - 72 hours postoperative VAS score,Morphine use 24-48 hours postoperative amount of postoperative morphine use	—

Secondary

Measure	Time frame
Range of knee motion (ROM) 24-72 hours postoperative degree,length of hospital stay 24-72hour day,blood loss 24-72 hours postoperative calculated blood loss (cc)	—

Countries

Thailand

Contacts

Public ContactArtit Laoreungthana

Faculty of Medicine, Naresuan University

artitlao@gmail.com0851102799

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026