Effect of dexmedetomidine on postoperative shoulder pain in patients undergoing laparoscopic liver resection: a randomized controlled trial

Status

Unknown

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211201004

Enrollment

Registered

2021-12-01

Start date

2021-11-17

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shoulder pain laparoscopic liver resection Dexmedetomidine Dexmedetomidine laparoscopic surgery laparoscopic liver resection shoulder pain shoulder tip pain post laparoscopic pain neuropathic pain opioid sparing

Interventions

Dexmedetomidine 1 mcg/kg infusion in 1 hr,NSS 20 ml Infusion in 1 hr

Active Comparator Drug,Placebo Comparator Drug

Dexmedetomidine,Normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patient undergoing elective laparoscopic liver resection 2. Age 18-70 year 3. American Society of Anesthesiology Physical Status (ASA) I-III

Exclusion criteria

Exclusion criteria: 1. Allergic to study drug 2. Having cardiovascular, respiratory, endocrine system conditions 3. Using sleep medication or pain medication 4. Alcohol or drug abuse 5.Malignant hyperthermia 6. Immunocompromised host

Design outcomes

Primary

Measure	Time frame
Incidence of shoulder pain post operative 0-48 hours Incidence , pain score in Numeric rating scale	—

Secondary

Measure	Time frame
Incisional pain post operative 0-48 hr pain score in Numeric rating scale,Morphine consumption post operative 0-48 hr amount of morphine,Time to extubatne post operative 0 hr Duration,Liver function test at 24,48 hr Laboratory data	—

Countries

Thailand

Contacts

Public ContactBowonkanok Ngamcheun

Faculty of medicine chulalongkorn university

dukdikddd@gmail.com0869881482

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026