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Rate and Time to recovery of adrenal insufficiency in Diffuse Large B cell Lymphoma patients after treatment with chemotherapy consisting of high dose corticosteroid

Rate and Time to recovery of adrenal insufficiency in Diffuse Large B cell Lymphoma patients after treatment with chemotherapy consisting of high dose corticosteroid

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20211126002
Enrollment
67
Registered
2021-11-26
Start date
2020-02-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients 18 years and older who were diagnosis DLBCL participating in the research project &#039

Interventions

The patients 18 years and older who were diagnosis DLBCL participating in the research project &#039
Incidence of Adrenal Insufficiency in Diffuse Large B-cell Lymphoma Patients after Treatment with the 5th Chemotherapy Cycle Consisting of High Dose Corticosteroid &#039
Adrenal insufficiency was detected by doing 1 mcg ACTH stimulation test and receiving R-CHOP chemotherapy regimen.
Other

Sponsors

Siriraj Hospital Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Diagnosis DLBCL participating in the research project ''Incidence of Adrenal Insufficiency in Diffuse Large B-cell Lymphoma Patients after Treatment with the 5th Chemotherapy Cycle Consisting of High Dose Corticosteroid'' 2. The patient 18 years and older and participate project by sign ICF.

Exclusion criteria

Exclusion criteria: 1.The patient had a history of adrenal insufficiency before starting chemotherapy in the previous 180 days. 2.The patient has a history of CT results showing that nodules in the adrenal glands were present. 3.The patient has a history of drugs steroids use. or suspected drugs steroids were an during the 180 days prior to participation in the study.

Design outcomes

Primary

MeasureTime frame
Rate and Time to recovery of adrenal insufficiency in Diffuse Large B cell Lymphoma patients after treatment with chemotherapy consisting of high dose corticosteroid 30 days after the completion of chemotherapy regimen R-CHOP The recovery rate of adrenal function was in patients with adrenal insufficiency.

Secondary

MeasureTime frame
How long it adrenal glands to return to normal After stopping CHOP/R-CHOP chemotherapy in patients with DLBCL lymphoma After the completion of chemotherapy . The recovery time of adrenal function was in patients with adrenal insufficiency

Countries

Thailand

Contacts

Public ContactSirinart Sirinvaravong

Division of Endocrinology & Metabolism.

Sirinart.sir@mahidol.ac.th0816222293

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026