The patients 18 years and older who were diagnosis DLBCL and receiving high dose corticosteroid -containing chemotherapy regimen R-CHOP. Incidence of Adrenal Insufficiency in Diffuse Large B-cell Lymphoma Patients after Treatment with the 5th Chemotherapy Cycle Consisting of High Dose Corticosteroid .
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Diagnosis DLBCL and receiving high dose corticosteroid -containing chemotherapy regimen R-CHOP. Who received treatment at the Department of Hematology of Siriraj Hospital from February 15, 2019 to February 14, 2021. 2.The patients 18 years and older and participate project by sign ICF.
Exclusion criteria
Exclusion criteria: 1.The patient has a history of Adrenal Insufficiency before. or currently receiving treatment. 2.The patient has a history of CT results showing that nodules in the adrenal glands were present. 3.The patient has a history of drugs steroids use. or suspected drugs steroids were an prior to participating in the research. and during the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of adrenal insufficiency in patients with DLBCL lymphoma while receiving chemotherapy. First clinical visit and after Treatment with the 5th Chemotherapy. The ACTH stimulation test is normal . | — |
Secondary
| Measure | Time frame |
|---|---|
| Factors contributing to adrenal insufficiency in DLBCL lymphoma patients. First clinic visit From medical record | — |
Countries
Thailand
Contacts
Division of Endocrinology & Metabolism