Differences in CD34, CD68, CD11c and CD163 Expression in Placentas from Pregnancies with and without Gestational Diabetes Mellitus

Differences in CD34, CD68, CD11c and CD163 Expressions in Placentas of Normal and Gestational Diabetes Mellitus Pregnancies

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20211122003

Enrollment

Registered

2021-11-22

Start date

2021-11-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes mellitus leads to changes in placental expressions in CD34, CD68, CD11c and CD163. Gestational diabetes mellitus, Immunohistochemistry, Placental expression.

Interventions

Placentas of pregnant women with gestational diabetes mellitus.,Placentas of healthy pregnant women.

Basic Science,Basic Science

Gestational diabetes mellitus,Normal pregnancy

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or older. 2. Term delivery (37 weeks of gestation or more). 3. Willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Multifetal pregnancies. 2. Having fetus with severe congenital or chromosomal abnormalities. 3. Having placental adherens. 4. HIV infection.

Design outcomes

Primary

Measure	Time frame
CD34 expression At the time of delivery Number of vessels per villus	—

Secondary

Measure	Time frame
CD68 expression At the time of delivery Number of positive staining per 10 photos,CD11c expression At the time of delivery Number of positive staining per 10 photos,CD163 expression At the time of delivery Number of positive staining per 10 photos	—

Countries

Thailand

Contacts

Public ContactChadakarn Phaloprakarn

Faculty of Medicine Vajira Hospital

chadakarn_pt@yahoo.com6622443405

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026