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An open-label, pilot study evaluating the efficacy of a lip balm containing panthenol and bisabolol as a monotherapy for the treatment of mild to moderate cheilitis

An open-label, pilot study evaluating the efficacy of a lip balm containing panthenol and bisabolol as a monotherapy for the treatment of mild to moderate cheilitis

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20211122002
Enrollment
20
Registered
2021-11-22
Start date
2020-10-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients diagnosed with mild to moderate cheilitis lip balm, panthenol, bisabolol, cheilitis, treatment

Interventions

Enrolled patients were treated with a lip balm containing panthenol and bisabolol (Eucerin Aquaphor SOS lip care) for 8 weeks. They were instructed to apply the lip balm to the lips twice a day, in th
Experimental Other
Patients treated with a lip balm containing panthenol and bisabolol

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or older 2. Patients who were diagnosed with mild to moderate cheilitis by dermatologists

Exclusion criteria

Exclusion criteria: (i) patients with other dermatologic diseases of the lips, (ii) patients with a history of contact allergy to panthenol and bisabolol, (iii) patients applied topical corticosteroids or topical calcineurin inhibitors at the lips 1 week prior to inclusion, (iv) patients taking oral corticosteroids 2 weeks prior to enrollment, and/or (v) pregnant or lactating patients

Design outcomes

Primary

MeasureTime frame
The efficacy of a lip balm containing panthenol and bisabolol baseline, week 2, week 4, and week 8 ICGS score

Secondary

MeasureTime frame
The safety of a lip balm containing panthenol and bisabolol baseline, week 2, week 4, and week 8 Adverse events,Physician and patient satisfaction week 8 Product satisfaction score

Countries

Thailand

Contacts

Public ContactWaranya Boonchai

Faculty of Medicine Siriraj Hospital, Mahidol University

wboonchai@yahoo.com024194333

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026