Acute kidney injury in patients with cirrhosis requiring hospitalization cirrhosis acute kidney injury novel biomarker Liver type Fatty Acid Binding Protein Neutrophil Gelatinase Associated Lipocalin
Conditions
Interventions
Patients with cirrhosis and acute kidney injury, diagnosis by clinical and laboratory parameters, imaging, and/or pathology
Diagnostic
Cirrhosis with acute kidney injury patients
Sponsors
Ratchadapisek Sompoch Funding, Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Known diagnosis of cirrhosis 2. Presence of risk of acute kidney injury, including gastrointestinal bleeding, bacterial infection, diarrhea, vomiting, poor intake, large-volume paracentesis, excessive diuretics usage, taking nephrotoxic drugs, and acute decompensation
Exclusion criteria
Exclusion criteria: 1. Prior liver or kidney transplantation 2. End-stage renal disease with renal replacement therapy at the time of enrollment 3. Acute interstitial nephritis 4. Acute glomerulonephritis 5. Post-renal acute kidney injury 4. Current use of immunosuppressive agents other than treatment of severe alcoholic hepatitis 5. Severe extrahepatic disease 6. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute kidney injury At 7 days after hospitalization Serum creatinine | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality At 28 days after hospitalization Death | — |
Countries
Thailand
Contacts
Public ContactSalisa Wejnaruemarn
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed