Immunogenicity of the third COVID-19 vaccine booster dose in adults with completed 2 doses as recommended by the ministry of public health

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20211120002

Enrollment

300

Registered

2021-11-20

Start date

2021-11-05

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Thai individuals aged 18 years and above immunogenicity, COVID-19. vaccine, booster

Interventions

Booster with AZD1222 in individuals vaccinated with two-dose BBIBP-CorV at 3-6 months post second vaccination.,Booster with BNT162b2 in individuals vaccinated with two-dose BBIBP-CorV.,Booster with mR

Active Comparator Biological/Vaccine,Active Comparator Biological/Vaccine,Active Comparator Biological/Vaccine,Active Comparator Biological/Vaccine,Active Comparator Biological/Vaccine,Active Comparat

Booster with AZD1222 in individuals vaccinated with two-dose BBIBP-CorV,Booster with BNT162b2 in individuals vaccinated with two-dose BBIBP-CorV,Booster with mRNA-1273 in individuals vaccinated with t

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Healthy Thai individuals above 18 years of age 2. Not previously infected with COVID-19 3. Provide informed consent

Exclusion criteria

Exclusion criteria: 1. Previously infected with COVID-19 2. Immunocompromised individuals

Design outcomes

Primary

Measure	Time frame
immunogenicity day 14 and 28 post booster anti- receptor-binding domain of SARS-CoV-2	—

Secondary

Measure	Time frame
neutralizing activities against variants day 14 and 28 post booster sVNT,T cell response dat 14 and day 28 post boost Quantiferon SARS-CoV-2	—

Countries

Thailand

Contacts

Public ContactYong Poovorawan

Chulalongkorn University

yong.p@chula.ac.th022564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026